Wuxi Beta: Focus on Research and Development of "Carp into Dragon"

This newspaper reporterLiu Xiao

Website:http://cnepaper.com/jyrbszb/html/2019-03/01/content_5_1.htm

Recently, Wuxi Beta Pharmaceutical Technology Co., Ltd., located in Jiangyin Biomedical Accelerator, signed a cooperation agreement on scientific and technological services with Sichuan Kelun Pharmaceutical Research Institute, a subsidiary of Kelun Pharmaceutical. The head of the new drug research and development department of the Sichuan Kelun Pharmaceutical Research Institute recognized Wuxi Beta's radioisotope labeling work and believed that Wuxi BetaIn 2018, the three small molecular compounds labeled with carbon -14(C-14) and tritium (H-3) isotopes for Sichuan Kelun Pharmaceutical Research Institute are more efficient, cheaper and more convenient to communicate than similar foreign products. We are willing to establish a long-term cooperative relationship with Wuxi Beta.

　On Wuxi Beta's customer list are Sichuan Kelun Pharmaceutical Research Institute, Jiangsu Hengrui Pharmaceutical, Jiangsu Haosen Pharmaceutical, Nanjing Shenghe Pharmaceutical, Beijing Sailintai Pharmaceutical, Fujian Haixi Pharmaceutical and other leading enterprises in new pharmaceutical research and development, as well as Qingdao Qingyuan and other leading enterprises in pesticide research and development.In 2018, Wuxi Beta provided the above companies with more than 10 successful markers for new drugs. Since then, my country's new drug research has ended the history of sending it abroad for isotope labeling, which has been well received by customers.

Isotope labeling is an important aspect of the peaceful use of nuclear energy, and it is also an important part of the nuclear industry serving medicine, pesticides, environmental protection industries, the national economy and people's lives. Isotope technology and its application is an important milestone in the history of human civilization. Its application level is an important symbol of a country's comprehensive national strength and a key development field of a world power. With the discovery of heavy hydrogen isotopes and artificial radionuclides, isotope tracer method is widely used in life science, medicine, chemistry and other fields. A communiqué of the International Atomic Energy Agency states:"In terms of the breadth of the impact on technology, it is possible that only modern electronics and data processing can be compared to isotopes."

Ten years to grind a sword, the bench can sit ten years cold. Wuxi Beta Pharmaceutical Technology Co., Ltd. was founded by Dr. Li Gang, winner of the Second Prize of National Science and Technology Progress Award and a returned entrepreneur from the United States,In November 2008, it entered the Biopharmaceutical Industrial Park of Jiangyin High-tech Zone. It is a leading enterprise in China specializing in the research and development and labeling services of carbon -14, carbon -13 and other isotope labeled compounds. The company's main direction is to provide "high, fine, lack" carbon -14, carbon -13 and other isotope labeling tracer technology services for the pharmaceutical, pesticide research and development industry and medical testing industry, so as to carry out drug generation, clinical, environmental research and disease testing.

Dr. Li Gang said that in the ten-year arduous and lonely research and development process, without the strong support of relevant departments in Jiangyin in office space, talent introduction, project application, etc., Wuxi Beta may not be able to support it until now. The Wuxi Beta R & D team with Dr. Li Gang as the core, with the enthusiastic help and guidance of academicians such as Zhou Yongmao and industry experts, and with the support of Jiangyin Science and Technology Fund, Wuxi Leading Talent Plan, Changsha High-level Talent Plan, Jiangsu Science and Technology Support Plan and the Innovation Fund of the Ministry of Science and Technology, has been focusing on research and development for ten years, forging ahead and solving the problem of carbonBottlenecks in the preparation and supply of -14 source materials and labeled precursor compounds; overcome the technical difficulties in the preparation and labeling of carbon -14 labeled key compounds; and realize the localization of urea-14C and urea-13C, the key raw materials for the detection of Helicobacter pylori in the stomach as the "gold standard. At the same time, it also conquered the preparation technology of isotope internal standard for neonatal genetic metabolic disease screening and vitamin D deficiency detection, breaking a number of international import restrictions at one stroke and realizing domestic substitution. In the context of the international trade war, Chinese companies have become more confident in the above areas. Not only that, in the field of carbon -14, Wuxi Beta has all the technologies of the entire industrial chain of "source materials-marking precursor compounds-marking service technology", which is the only and most competitive in the world. It can become a reliable marking service partner for pharmaceutical and pesticide development enterprises, and a strong backing to ensure its innovation and development. Wuxi Beta is also actively entering the international market, providing all-round and scarce isotope labeling products and tracer technology services for foreign enterprises, and is committed to building a leading enterprise in the international carbon -14 labeling field.

Recently, Wuxi Beta has also been invited by the Medical Device Evaluation Center of the State Food and Drug Administration to participate in the discussion and formulation of the guidelines for the registration of isotope-labeled testing reagents for screening of neonatal genetic and metabolic diseases, and to participate in the formulation of agricultural industry standards for the pesticide metabolism and residue testing guidelines in livestock and poultry at the invitation of the Pesticide Control Institute of the Ministry of Agriculture and Rural Affairs. Practice has proved that as long as we focus on R & D and master the key core technologies, small companies can also have the right to speak in the industry, and small enterprises can also make great achievements.

Ten years of hard work, finally ushered in the harvest fruit. Orders from leading pharmaceutical and pesticide research and development companies poured in, so much so that Wuxi Beta transferred employees from its Changsha subsidiary to Jiangyin Laboratory to help complete the orders. At the same time, it began to recruit doctors and masters from prestigious universities such as Peking University to join the company. Wuxi BetaIn 2018, the company achieved its first profit in ten years.

Good wind relies on strength, and opportunities only favor enterprises that are prepared. Wuxi Beta Station has reached the outlet of the outbreak of the high-tech sub-industry of isotope marking tracing. Currently, carbon-14 labeled compounds and tracer technology are widely used in the study of metabolism of new drugs. In addition to the use of carbon -14 markers in the research and development of human drugs, the research and development of new pesticides must also use carbon -14 tracer technology to better protect the environment and reduce the harm of pesticide residues from the source.

Under the good situation of frequent favorable national policies and regulations, this year, Wuxi Beta will make steady progress, take advantage of the situation, and further improve carbon-14, carbon -13 and other isotope business bigger and stronger, to build atomic energy application and isotope labeling tracer characteristic industrial highland, international carbon -14 production and application leading enterprises, so that isotope atomic energy for the benefit of China's new medicine, new pesticide research and development and precision medical testing, for the benefit of human health and ecological environmental protection.

At present, Wuxi Beta is accelerating the pace of financing, further expanding production capacity; strengthen cooperation and development, so that a number"Gold standard" technology as soon as possible to enter the domestic and foreign markets, aiming to land on the board, to create a "unicorn" enterprise in the field of biomedicine.

Website:http://cnepaper.com/jyrbszb/html/2019-03/01/content_5_1.htm