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Information List

Ministry of Agriculture "Guidelines for Metabolic Testing of Pesticides in Plants" (draft for comments)

2018-10-25

Excerpt: Issued by: Ministry of Agriculture of China Issued on May 7, 2017. Isotope labeling synthesis of 3.2 pesticides The process of isotope labeling synthesis of pesticide molecules (stable skeletons) using radioactive and (or) stable isotopes to obtain 13C, 14C, 15N and 35S labeled pesticide compounds. In general, 14C is preferred, and when the molecule contains no carbon atoms or only unstable carbon-containing side chains, 35S or other radioactive isotopes are contemplated. Stable isotopes (such as 13C and 15N) are used together with radioactive isotopes to help metabolism

Technical Summary Exchange Meeting of China Nuclear Power Research and Design Institute Held in Chengdu

2018-10-25

On October 29, 2016, China Nuclear Power Research and Design Institute held a technical summary exchange meeting in Chengdu, announcing the success of the localization of C14 source materials. In September 2010, under the coordination and guidance of Academician Zhou Yongmao and Academician Sun Yufa, Wuxi Beta Pharmaceutical Technology Co., Ltd. established a cooperative relationship with China Nuclear Power Research and Design Institute. After 6 years of unremitting efforts, it finally overcame the difficulties. The localization of C14 source materials was realized, and a solution was established for the international shortage of C14.

Jiangyin High-tech Zone Established Fourth Nobel Prize Winner Research Institute

2018-07-19

Reprint: Binhai High-tech Network News Binhai High-tech Network News Recently, Wuxi Beta Pharmaceutical Technology Co., Ltd. joined hands with Nobel Prize winner Professor Robert Grubb to set up the Grubb Isotope Labeling China (Jiangyin) Research Institute in Jiangyin High-tech Zone, and the "Academician Zhou Yongmao Workstation" of the Chinese Academy of Engineering was also set up at the same time. So far, Jiangyin has introduced five Nobel laureates and established four Nobel laureates. In recent years, Jiangyin City has attached great importance to the work of scientific and technological talents, and has fully implemented the "High-level Talent Gathering Plan" including the "Nobel Prize Winners Gathering Plan", "Academician Gathering Plan", and "Overseas Engineer Gathering Plan". This time with the grid

Wuxi Beta and Shanghai Medissi Biotechnology Co., Ltd. to establish a cooperative relationship

2018-10-25

On June 24, 2016, Wuxi Beta Pharmaceutical Technology Co., Ltd. and Shanghai Medisi Biotechnology Co., Ltd. signed a framework agreement to complement each other's advantages and do their best to cooperate in the development of C14 labeling of Chinese medicine and animal drug generation research. Actively promote the development of my country's new drug development industry.

Technical guidelines for non-clinical pharmacokinetic studies of drugs

2018-10-25

Excerpt: Release Unit: china food and drug administration Release Date: May 13, 2014 2. Selection of Radioisotope Labeling Methods Low-energy radioisotopes commonly used in ADME research of small molecule chemical drugs are carbon -14(14C) and tritium (3H). 14C labeling is the most commonly used, its biological background is low, biology almost no isotope effect and affect metabolism, rarely occur isotope exchange, sensitivity is higher than 3H and easy to quantify. Metabolically stable sites should be selected when labeling carbon -14 compounds. In vivo testing unless 14C labeling is very difficult or

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